Xiang-Ping Chu Selected Research

Acid Sensing Ion Channels

1/2021	Acid-Sensing Ion Channel 1 Contributes to Weak Acid-Induced Migration of Human Malignant Glioma Cells.
1/2020	Monoclonal antibody as an emerging therapy for acute ischemic stroke.
1/2018	Hi1a as a Novel Neuroprotective Agent for Ischemic Stroke by Inhibition of Acid-Sensing Ion Channel 1a.
2/2017	Region specific contribution of ASIC2 to acidosis-and ischemia-induced neuronal injury.
2/2014	Acid-sensing ion channels contribute to neurotoxicity.
3/2012	N-glycosylation of acid-sensing ion channel 1a regulates its trafficking and acidosis-induced spine remodeling.
2/2012	Physiological and pathological functions of acid-sensing ion channels in the central nervous system.
1/2011	Modulation of acid-sensing ion channels: molecular mechanisms and therapeutic potential.
2/2007	Extracellular zinc protects against acidosis-induced injury of cells expressing Ca2+-permeable acid-sensing ion channels.
1/2007	Acid sensing ion channels--novel therapeutic targets for ischemic brain injury.

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Xiang-Ping Chu Research Topics

Disease

11	Acidosis 02/2017 - 07/2003
6	Stroke (Strokes) 01/2020 - 09/2004
4	Epilepsy (Aura) 01/2022 - 01/2011
4	Brain Injuries (Brain Injury) 01/2022 - 01/2007
3	Multiple Sclerosis 01/2022 - 01/2011
3	Ischemic Stroke 01/2020 - 01/2011
3	Inflammation (Inflammations) 01/2020 - 01/2011
3	Brain Ischemia (Cerebral Ischemia) 02/2012 - 09/2006
3	Ischemia 02/2012 - 09/2004
2	Glioma (Gliomas) 01/2021 - 02/2012
2	Neoplasms (Cancer) 01/2020 - 01/2019
2	Traumatic Brain Injuries (Traumatic Brain Injury) 02/2012 - 01/2011
2	Asthma (Bronchial Asthma) 10/2008 - 02/2006
1	Motor Disorders 05/2022
1	Substance-Related Disorders (Drug Abuse) 01/2022
1	Migraine Disorders (Migraine) 01/2022
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2022
1	Treatment-Resistant Depressive Disorder 01/2020
1	Major Depressive Disorder (Major Depressive Disorders) 01/2020
1	Cocaine-Related Disorders (Cocaine Addiction) 01/2019
1	Obesity 01/2019
1	Sudden Unexpected Death in Epilepsy 01/2019
1	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 01/2018
1	Nervous System Diseases (Neurological Disorders) 02/2012
1	Seizures (Absence Seizure) 02/2012
1	Pain (Aches) 01/2012
1	Acute Pain 01/2012
1	Pathologic Processes 01/2011
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/2007

Drug/Important Bio-Agent (IBA)

12	Acid Sensing Ion ChannelsIBA 01/2021 - 09/2004
4	AcidsIBA 01/2021 - 09/2006
3	Ion Channels (Ion Channel)IBA 01/2019 - 01/2011
3	Protons (Proton)IBA 02/2012 - 01/2011
3	CationsIBA 01/2011 - 07/2003
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2011
2	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2020 - 01/2018
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2020 - 02/2011
2	Pharmaceutical PreparationsIBA 01/2018 - 02/2006
2	ZincIBA 01/2012 - 02/2007
2	Anti-Asthmatic Agents (Antiasthmatic Drugs)IBA 10/2008 - 02/2006
2	Glutamate Receptors (Glutamate Receptor)IBA 05/2006 - 09/2004
2	CalciumIBA 09/2004 - 07/2003
1	Cholinergic Agents (Cholinergics)IBA 05/2022
1	Antidepressive Agents (Antidepressants)IBA 01/2020
1	Therapeutic UsesIBA 01/2020
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020
1	Monoclonal AntibodiesIBA 01/2020
1	NAD (NADH)IBA 01/2019
1	Sirtuin 1IBA 01/2019
1	Nicotinamide PhosphoribosyltransferaseIBA 01/2019
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2019
1	Neuroprotective AgentsIBA 01/2018
1	Peptides (Polypeptides)IBA 01/2018
1	Spider Venoms (Venom, Spider)IBA 01/2018
1	DisulfidesIBA 01/2018
1	Ligand-Gated Ion ChannelsIBA 02/2014
1	Lactic Acid (Lactate)FDA LinkGeneric 02/2012
1	Retinaldehyde (Retinal)IBA 02/2012
1	SpermineIBA 02/2011
1	PolyaminesIBA 02/2011
1	NeuropeptidesIBA 01/2011
1	OvalbuminIBA 10/2008
1	Anti-Allergic Agents (Antiallergic Agents)IBA 10/2008
1	Small Interfering RNA (siRNA)IBA 11/2007
1	Acid Sensing Ion Channel BlockersIBA 09/2004
1	Excitatory Amino Acid AntagonistsIBA 09/2004
1	Glutamic Acid (Glutamate)FDA Link 09/2004

Therapy/Procedure

3	Therapeutics 01/2020 - 01/2018
2	Ketogenic Diet 01/2020 - 01/2019
1	Transcranial Magnetic Stimulation 01/2020